Regulators are racing to rein in the power of large digital platforms so that fast-evolving markets remain open and contestable. Global digital markets will increasingly be the subject of national and regional regulation. There are several open questions: will first-mover EU regulation be copied across the world? And will it promote or frustrate the roll-out of new technologies in Europe? Should regulations impose general or tailor-made requirements? To what extent will new digital issues, such as generative artificial intelligence (Gen AI), be regulated or fall to traditional antitrust enforcement? Our panel will discuss the developing global regulatory landscape and consider the compliance burden and opportunities.